HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → (R)-(-)-5-Bromo-2-(1-methylheptyloxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | (R)-(-)-2-(1Methylheptyloxy)benzonitrile | HCID 21308782 | — |
| Reactant | (S)-(+)-5-Bromo-2-(2-methylbutyloxy)benzonitrile | HCID 53787839 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | (R)-(-)-5-Bromo-2-(1-methylheptyloxy)benzonitrile | HCID 53905579 | — |
Reaction Steps
Quantities: compound 40 (12.34 g, 0.054 mol), bromine (17.15 g, 0.0107 mol), chloroform (100 ml). The experimental procedure was as described for the preparation of compound 41. The crude product was purified by column chromatography (20% petrol/dichloromethane) to give a fawn oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06278028B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-2852928170f24de9af50cd9536d74e04 |
| Source note | uspto-grants-2001_08 |