反应详情

A suspension of the 4′-chlorobiphenyl-4-sulfonic acid in 100 mL of thionyl chloride is heated at reflux for 6 h, and the resulting homogeneous solution is then cooled to RT. The mixture is concentrated under reduced pressure and the residue is triturated with diethyl ether and dried to afford 9.8 g (95%) of 4′-chlorobiphenyl-4-sulfonyl chloride as an off-white solid.

1. temperatureis heated
2. temperatureat reflux for 6 h
3. concentrationThe mixture is concentrated under reduced pressure
4. customthe residue is triturated with diethyl ether
5. customdried