HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4'-Chlorobiphenyl-4-sulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4'-Chloro[1,1'-biphenyl]-4-sulfonic acid | HCID 15429141 | — |
| Product | 4'-Chlorobiphenyl-4-sulfonyl chloride | HCID 2794745 | 95% |
Reaction Steps
A suspension of the 4′-chlorobiphenyl-4-sulfonic acid in 100 mL of thionyl chloride is heated at reflux for 6 h, and the resulting homogeneous solution is then cooled to RT. The mixture is concentrated under reduced pressure and the residue is triturated with diethyl ether and dried to afford 9.8 g (95%) of 4′-chlorobiphenyl-4-sulfonyl chloride as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06277987B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-b8add0fe30734fef9ae64c35dd7ef0ed |
| Source note | uspto-grants-2001_08 |