Hydrochloric Acid → HCID 69288519, compound

Participants

Reaction Steps

A solution of the title A compound, (2R)-(t-butyloxycarbonylamino)-4-morpholin-4-yl-4-oxobutyric acid benzyl ester (2.91 g, 7.42 mmol) in 50 mL of ethyl acetate is saturated with hydrogen chloride gas for 15 min. The reaction is sealed and stirred for 3 h at RT. The solvent is evaporated to afford 2.27 g (93%) of (2R)-amino-4-morpholin-4-yl-4-oxobutyric acid benzyl ester hydrochloride as a white solid.

Provenance & Evidence