m-Chloroperbenzoic acid → HCID 21138136, compound

HRID 651508Notes

Reaction equation

HRID 651508 reaction equation
[CH:1]1([O:6][C:7]2[CH:24]=[CH:23][C:22]3[C@@H:21]4[C@H:12]([C@H:13]5[C@@:17]([CH2:19][C@@H:20]4[C:25]4[CH:30]=[CH:29][C:28]([O:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][S:37]([CH2:39][CH2:40][CH2:41][C:42]([F:48])([F:47])[C:43]([F:46])([F:45])[F:44])=[O:38])=[CH:27][CH:26]=4)([CH3:18])[C@@H:16]([OH:49])[CH2:15][CH2:14]5)[CH2:11][CH2:10][C:9]=3[CH:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.ClC1C=CC=C(C(OO)=[O:58])C=1>>[CH:1]1([O:6][C:7]2[CH:24]=[CH:23][C:22]3[C@@H:21]4[C@H:12]([C@H:13]5[C@@:17]([CH2:19][C@@H:20]4[C:25]4[CH:30]=[CH:29][C:28]([O:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][S:37]([CH2:39][CH2:40][CH2:41][C:42]([F:47])([F:48])[C:43]([F:44])([F:45])[F:46])(=[O:58])=[O:38])=[CH:27][CH:26]=4)([CH3:18])[C@@H:16]([OH:49])[CH2:15][CH2:14]5)[CH2:11][CH2:10][C:9]=3[CH:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 21138134HCID 21138134, compound

Product 1

HCID 21138136HCID 21138136, compoundYield 79.4%

Procedure

By operating as in Example 56 using at the start 698 mg of the product obtained in Example 68 and 228 mg of metachloro perbenzoic acid, 567 mg of expected product is obtained. M.p.=166° C.

Sources & evidence

ORD record
ord-a961091a338148828fa8a9e1aa03f097
Source dataset
uspto-grants-2001_08
Patent number
US06281204B1

Reaction notes

Loading…