2-Chlorophenol → HCID 581793, compound

HRID 651555Notes

Reaction equation

HRID 651555 reaction equation
ClCCC(Cl)=O.[Cl:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[O:14][C:15](=[O:19])[CH2:16][CH2:17][Cl:18].ClC1C=CC=CC=1O>>[Cl:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[O:14][C:15](=[O:19])[CH2:16][CH2:17][Cl:18]

Participants

3

Reactant 2

HCID 72452-ChlorophenolHCID 86757274HCID 86757274, compound

Product 1

HCID 581793HCID 581793, compound

Conditions

Temperature
75 °C

Procedure

3-Chloro-propanoic acid 2-chlorophenyl ester 3-chloropropionylchloride (14 ml) was added to 2-chlorophenol (18.18 g) and the mixture was stirred and heated at 60° C. for 1 hour, at 75° C. for 1 hour and left over the weekend at ambient temperature. The compound was purified by destination in vacuo to give 19,7 g (b.p. 91-94° C. 0.08 mm Hg) of 3-chloro-propanoic acid 2-chlorophenyl ester.

Workup

  1. waitleft over the weekend at ambient temperature
  2. customThe compound was purified by destination in vacuo

Sources & evidence

ORD record
ord-908a8fad9adb4bc39f1673c8792fa82f
Source dataset
uspto-grants-2001_08
Patent number
US06281243B1

Reaction notes

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