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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 651568Generated: October 31, 2026

3-(5,6,7,8-Tetrahydro-1-naphthalenyloxy)-pyrrolidine hydrochloride → (3S)-3-[(2,3--Dihydro-5-methoxy-1H-inden-4-yl)oxy]pyrrolidine hydrochloride

https://huagongshe.com/reaction/651568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(5,6,7,8-Tetrahydro-1-naphthalenyloxy)-pyrrolidine hydrochlorideHCID 14497377—
Reactant3-[(5,6,7,8-Tetrahydro-1-naphthalenyl)oxy]-1-(phenylmethyl)-pyrrolidineHCID 22451509—
Product(3S)-3-[(2,3--Dihydro-5-methoxy-1H-inden-4-yl)oxy]pyrrolidine hydrochlorideHCID 9881884—

Reaction Steps

3-[(5,6,7,8-Tetrahydro-1-naphthalenyl)oxy]-pyrrolidine hydrochloride m.p. 207° C., starting from 3-[(5,6,7,8-tetrahydro-1-naphthalenyl)oxy]-1-(phenylmethyl)-pyrrolidine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06281243B1
Source datasetuspto-grants-2001_08
ORD IDord-ca9e66eefe3149e8a83749b410337d64
Source noteuspto-grants-2001_08