HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate → HCID 54264036, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate | HCID 10750535 | — |
| Reactant | 6-(Bromomethyl)-2-chloroquinoline | HCID 11276889 | — |
| Product | HCID 54264036 | HCID 54264036 | — |
Reaction Steps
The title compound is prepared from (2-oxopyrrolidin-3-(S)-yl)-carbamic acid tert-butyl ester as described in EXAMPLE 1, Part H using 6-bromomethyl-2-chloro-quinoline in place of 7-bromomethyl-1-chloroisoquinoline. The crude product is purified by column chromatography eluting with a gradient of 2% MeOH/CH2Cl2 to 4% MeOH/CH2Cl2 to afford the title compound as a beige solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06281227B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-c4ca9aff67c247489647aa8d3fe48b13 |
| Source note | uspto-grants-2001_08 |