N-(Diphenylmethyl)methylamine → Methyl (n-diphenylmethyl-n-methylsulfamoyl)acetate

HRID 651698Notes

Reaction equation

HRID 651698 reaction equation
[CH3:1][NH:2][CH:3]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.Cl[S:17]([CH2:20][C:21]([O:23][CH3:24])=[O:22])(=[O:19])=[O:18]>>[C:10]1([CH:3]([C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)[N:2]([CH3:1])[S:17]([CH2:20][C:21]([O:23][CH3:24])=[O:22])(=[O:19])=[O:18])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 411467N-(Diphenylmethyl)methylamineHCID 11435213Methyl (chlorosulfonyl)acetate

Product 1

HCID 20681419Methyl (n-diphenylmethyl-n-methylsulfamoyl)acetateYield 37%

Procedure

The subtitle compound (3.05 g, 37%) was prepared as a clear brown oil from N-methyl benzhydrylamine (prepared according to the method of Z. Horii, T Sakai and Inoi, Pharm Bull., 1955, 3, 159) (10.7 g, 50.7 mmol) and methyl chlorosulfonylacetate (4.27 g, 24.7 mmol), using the method of Example 1(a).

Workup

  1. customprepared

Sources & evidence

ORD record
ord-94b65b19089241e7b12f702a48d48957
Source dataset
uspto-grants-2001_08
Patent number
US06281357B1

Reaction notes

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