Ammonia → (n-Diphenylmethyl-n-methylsulfamoyl)acetamide

HRID 651699Notes

Reaction equation

HRID 651699 reaction equation
[C:1]1([CH:7]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[N:8]([CH3:17])[S:9]([CH2:12][C:13](OC)=[O:14])(=[O:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH3:24]>>[C:1]1([CH:7]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[N:8]([CH3:17])[S:9]([CH2:12][C:13]([NH2:24])=[O:14])(=[O:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 20681419Methyl (n-diphenylmethyl-n-methylsulfamoyl)acetate

Product 1

HCID 21709118(n-Diphenylmethyl-n-methylsulfamoyl)acetamideYield 90%

Procedure

The subtitle compound (2.62 g, 90%) was prepared as a white solid from aqueous ammonia solution (10 ml, s.g.=0.88) and methyl (N-diphenylmethyl-N-methylsulfamoyl)acetate (from step (a), 3.05 g, 9.2 mmol), using the method of Example 1(b). m.p. 110-115° C.

Sources & evidence

ORD record
ord-43f16bb76df34dcca17e4b167d7544a3
Source dataset
uspto-grants-2001_08
Patent number
US06281357B1

Reaction notes

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