Ethanol → HCID 283782, compound

HRID 651960Notes

Reaction equation

HRID 651960 reaction equation
C(O)C.[CH3:4][C:5]1[CH:12]=[C:11]([CH3:13])[CH:10]=[C:9]([CH3:14])[C:6]=1[CH:7]=O.C([O-])(=O)C.[Na+].Cl.[NH2:21][OH:22]>O>[CH3:4][C:5]1[CH:12]=[C:11]([CH3:13])[CH:10]=[C:9]([CH3:14])[C:6]=1[CH:7]=[N:21][OH:22]

Participants

6

Reactant 4

HCID 702EthanolHCID 102542,4,6-TrimethylbenzaldehydeHCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium Acetate

Product 1

HCID 283782HCID 283782, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

To 120 ml of ethanol and 60 ml of water were added 29.6 g (0.2 mole) of 2,4,6-trimethylbenzaldehyde, 32.8 g (0.4 mole) of sodium acetate and 20.7 g (0.3 mole) of hydroxylamine hydrochloride, and the mixture was heated under reflux for 2 hours. After the reaction, the reaction mixture was added to 500 ml of water. The precipitated crystals were collected by filtration to give 28 g (0.17 mole) of 2,4,6-trimethylbenzaldoxime.

Workup

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for 2 hours
  3. customAfter the reaction
  4. filtrationThe precipitated crystals were collected by filtration

Sources & evidence

ORD record
ord-609f41c72cc74ff0b7a7876446893ff5
Source dataset
uspto-grants-1987_06
Patent number
US04670373

Reaction notes

Loading…