HRID65201

反应详情

EQUATION

反应方程式

HRID 65201 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

CONDITIONS

反应条件

温度
5 °C

PROCEDURE

实验过程

11.4 ml of phenyl chloroformate are added slowly to a solution of 12.7 g of 5-(2-chlorophenyl)-2-(4-hydroxypiperidino)pyrimidine (Example 4) in 50 ml of pyridine, cooled to 5° C. After the addition has ended, the mixture is heated at 60° C. for 3 hours.

WORKUP

后处理

  1. additionAfter the addition
  2. temperaturethe mixture is heated at 60° C. for 3 hours