反应详情

A solution of 14.1 g. ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoate and 6.4 g. 85% potassium hydroxide in 150 ml. 95% ethanol was heated at 75° for 5 hr. The reaction was diluted with 300 ml. water and adjusted to pH 3.5 with concentrated hydrochloric acid. The precipitate was filtered, dried, and crystallized from acetone to yield a white solid, m.p. 105°-107° C.

1. additionThe reaction was diluted with 300 ml
2. filtrationThe precipitate was filtered
3. customdried
4. customcrystallized from acetone
5. customto yield a white solid, m.p. 105°-107° C.