反应详情

1.7 Gram of this benzamide was liberated in an aqueous potassium carbonate solution, extracted with chloroform, dried over anhydrous sodium sulfate and concentrated. The thus-produced residue was dissolved in 50 ml of ethanol and then the solution was subjected to hydrogenolysis on 500 mg of 5% Pd - C. After the reaction was finished, the precipitated crystals were dissolved in hot methanol and the catalyst was filtered off. Then the solvent was distilled away and the residue was crystallized from ethanol to obtain 1.0 g of the titled compound. The characteristics of this compound were shown in Table 1. And, IR spectrum of this compound was shown in FIG. 1 of the accompanying drawings.

1. extractionextracted with chloroform
2. dry with materialdried over anhydrous sodium sulfate
3. concentrationconcentrated
4. dissolutionThe thus-produced residue was dissolved in 50 ml of ethanol
5. dissolutionthe precipitated crystals were dissolved in hot methanol
6. filtrationthe catalyst was filtered off
7. distillationThen the solvent was distilled away
8. customthe residue was crystallized from ethanol