HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-[4-[3-(1-Piperidinylmethyl)phenoxy]butyl]amino-1H-1,2,4-triazole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 178470502 | HCID 178470502 | — |
| Product | 5-[4-[3-(1-Piperidinylmethyl)phenoxy]butyl]amino-1H-1,2,4-triazole-3-carboxamide | HCID 178513858 | — |
Reaction Steps
A suspension of ethyl 5-[4-[3-(1-piperidinylmethyl)phenoxy]butyl]amino-1H-1,2,4-triazole-3-carboxylate (867 mg) in 0.88 ammonia (25 ml) was stirred at room temperature for 18 h. The mixture was evaporated and the residual solid was washed with boiling methanol to leave the title compound as a white solid (255 mg) m.p. 212°-4° dec.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04670448 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-14c83efbb5a6445a914eda5e07f698f2 |
| Source note | uspto-grants-1987_06 |