Thionyl Chloride → HCID 20199155, compound

Participants

Reaction Steps

A mixture of 1-methyl-5-[4-[3-(1-piperidinylmethyl)phenoxy]butyl]amino-1H-1,2,4-triazole-3-methanol (0.75 g) and thionyl chloride (4 ml) was stirred at room temperature for 2 h. The mixture was evaporated in vacuo and the residue was dissolved in chloroform and washed with sodium bicarbonate. The organic extract was dried and evaporated to give the title compound as an oil (0.75 g) T.l.c. System E Rf 0.65.

Provenance & Evidence