反应详情

An autoclave was charged with 10.0 g of 4-(2-fluorobenzoyl)-1-methylpiperidine and 14 ml of hydrazine hydrate. The reaction was heated at 150° for 20 hrs, cooled, and poured into water. The resultant solid was collected. The solid was recrystallized twice from toluene to yield 2.4 g (23.7%) of product, mp 168°-170° C.

1. temperatureThe reaction was heated at 150° for 20 hrs
2. temperaturecooled
3. customThe resultant solid was collected
4. customThe solid was recrystallized twice from toluene