Ammonia → HCID 20199615, compound

HRID 652225Notes

Reaction equation

HRID 652225 reaction equation
[CH:1]1([C:4]2[N:9]=[C:8]([C:10]([Cl:13])([Cl:12])[Cl:11])[N:7]=[C:6](C(Cl)(Cl)Cl)[N:5]=2)[CH2:3][CH2:2]1.[NH3:18]>O1CCCC1.O>[NH2:18][C:6]1[N:5]=[C:4]([CH:1]2[CH2:2][CH2:3]2)[N:9]=[C:8]([C:10]([Cl:13])([Cl:12])[Cl:11])[N:7]=1

Participants

5

Reactant 2

HCID 222AmmoniaHCID 201996132-Cyclopropyl-4,6-bis-trichloromethyl-1,3,5-triazine

Product 1

HCID 20199615HCID 20199615, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8028TetrahydrofuranSolvent

Procedure

71.2 g of 2-cyclopropyl-4,6-bis-trichloromethyl-1,3,5-triazine are dissolved in 70 ml of tetrahydrofuran, and at room temperature are added, with stirring, 300 ml of a concentrated aqueous ammonia solution. The reaction mixture is stirred for 30 minutes; it is then diluted with water, and the formed emulsion is extracted with ether. The ether phases are collected, dried, filtered and subsequently concentrated by evaporation. The residue crystallises and there remain 48 g of the crystalline title product, m.p. 111°-114° C.

Workup

  1. additionat room temperature are added
  2. stirringThe reaction mixture is stirred for 30 minutes
  3. extractionthe formed emulsion is extracted with ether
  4. customThe ether phases are collected
  5. customdried
  6. filtrationfiltered
  7. concentrationsubsequently concentrated by evaporation
  8. customThe residue crystallises

Sources & evidence

ORD record
ord-ab9961fe241d441fbd156a2df11937c2
Source dataset
uspto-grants-1987_06
Patent number
US04670559

Reaction notes

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