Sodium Methoxide → 2-Cyclopropyl-4-methoxy-6-(trichloromethyl)-1,3,5-triazine

HRID 652226Notes

Reaction equation

HRID 652226 reaction equation
[CH:1]1([C:4]2[N:9]=[C:8](C(Cl)(Cl)Cl)[N:7]=[C:6]([C:14]([Cl:17])([Cl:16])[Cl:15])[N:5]=2)[CH2:3][CH2:2]1.[CH3:18][O-:19].[Na+]>CO>[CH:1]1([C:4]2[N:9]=[C:8]([O:19][CH3:18])[N:7]=[C:6]([C:14]([Cl:17])([Cl:16])[Cl:15])[N:5]=2)[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 201996132-Cyclopropyl-4,6-bis-trichloromethyl-1,3,5-triazine

Product 1

HCID 201996182-Cyclopropyl-4-methoxy-6-(trichloromethyl)-1,3,5-triazine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 48 g of 2-cyclopropyl-4,6-bis-(trichloromethyl)-1,3,5-triazine in 200 ml of MeOH are added, with stirring, 4.9 g of sodium methylate, and the mixture is stirred for 1 hour at room temperature; it is then filtered and the filtrate is evaporated to dryness. The yield is 28.5 g of the title compound as a light-red oil, which solidifies after some time, m.p. 49°-51° C.

Workup

  1. filtrationit is then filtered
  2. customthe filtrate is evaporated to dryness

Sources & evidence

ORD record
ord-16fb1c70e63e4e61be89e234bb424404
Source dataset
uspto-grants-1987_06
Patent number
US04670559

Reaction notes

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