反应详情

5 g (about 0.05 moles) of 4-methyl-3-aminofurazan, 50 ml of ethyl ether and 4 ml of pyridine are then loaded into a 100 ml glass reactor. This is cooled to a temperature of from 0° to 10° C. and 5 ml (0.06 moles) of the chloride of cyclopropanecarboxylic acid are added under agitation. Heating is then carried out under reflux for about one hour. After cooling of the reaction mass, the ether is evaporated and the residual solid is transferred into about 100 ml of water. Slight heating is effected for about 30 minutes and then the mass is cooled and filtered, the solid being washed with water. The solid obtained is dried in an oven at 90° C.

1. additionare added under agitation
2. temperatureHeating
3. temperatureunder reflux for about one hour
4. temperatureAfter cooling of the reaction mass
5. customthe ether is evaporated
6. temperatureSlight heating
7. temperaturethe mass is cooled
8. filtrationfiltered
9. washthe solid being washed with water
10. customThe solid obtained
11. customis dried in an oven at 90° C.