HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Pyridin-3-yl)propan-1-amine → 4-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[3-(3-pyridinyl)propyl]butanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Pyridin-3-yl)propan-1-amine | HCID 13557523 | — |
| Reactant | 4-(4-Acetyl-3-hydroxy-2-propylphenoxy)butanoic acid | HCID 13753871 | — |
| Product | 4-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[3-(3-pyridinyl)propyl]butanamide | HCID 13912782 | — |
Reaction Steps
4-(4-Acetyl-3-hydroxy-2-propylphenoxy)butanoic acid was allowed to react with 3-pyridine propanamine according to procedure A and the product was purified by chromatography on silica gel to give 4-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[3-(3-pyridinyl)propyl]butanamide, the title compound, mp 97°-98° (from methylene chloride-ether) in 88% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04672066 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-712df246f5384098bd245e27dd749207 |
| Source note | uspto-grants-1987_06 |