Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 652485Generated: October 30, 2026

2-(Pyridin-4-ylsulfanyl)-ethylamine → 6-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[2-(4-pyridinylthio)ethyl]hexanamide

https://huagongshe.com/reaction/652485

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Pyridin-4-ylsulfanyl)-ethylamineHCID 13557535—
Reactant6-(4-Acetyl-3-hydroxy-2-propylphenoxy)hexanoic acidHCID 13753873—
Product6-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[2-(4-pyridinylthio)ethyl]hexanamideHCID 13912777—

Reaction Steps

6-(4-Acetyl-3-hydroxy-2-propylphenoxy)hexanoic acid was allowed to react with 2-(4-pyridinylthio)ethyl amine according to procedure A and the product was purified by crystallization from ethyl acetate-hexane to give 6-(4-acetyl-3-hydroxy-2-propylphenoxy)-N-[2-(4-pyridinylthio)ethyl]hexanamide, the title compound, mp 63°-65°, in 52% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04672066
Source datasetuspto-grants-1987_06
ORD IDord-cce1a38fccf841b1a0b86af1b4b42ac1
Source noteuspto-grants-1987_06