反应详情

Combine 6.1 g (0.03 mole) 1-chloro-4-(4-chlorobutyl)benzene with 2.5 g (0.03 mole) 1-methyl-1H-imidazole and heat at 120° C., following the course of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5). At the completion of the reaction, cool and triturate with ether, collect the solid and recrystallize from 50 ml hot acetone to obtain the title compound.

1. customthe course of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5)
2. customAt the completion of the reaction
3. temperaturecool
4. customtriturate with ether
5. customcollect the solid
6. customrecrystallize from 50 ml hot acetone