HuagongsheHuagongshe Chemistry Print Report · For research reference only
2',4'-Dihydroxy-3'-propylacetophenone → 4-[(4-Acetyl-3-hydroxy-2-propylphenoxy)methyl]-2-ethoxybenzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2',4'-Dihydroxy-3'-propylacetophenone | HCID 2775198 | — |
| Reactant | Benzoic acid, 4-(bromomethyl)-2-ethoxy-, ethyl ester | HCID 10589339 | — |
| Product | 4-[(4-Acetyl-3-hydroxy-2-propylphenoxy)methyl]-2-ethoxybenzoic acid ethyl ester | HCID 13912822 | — |
Reaction Steps
1-(2,4-dihydroxy-3-propylphenyl)ethanone was allowed to react with 4-(bromomethyl)-2-ethoxybenzoic acid ethyl ester according to the procedure of Example 69 and the product was purified by HPLC to give 4-[(4-acetyl-3-hydroxy-2-propylphenoxy)methyl]-2-ethoxybenzoic acid ethyl ester, the title compound, m.p. 92°-94° in 83% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04672066 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-a81bf4caf7614d4b826574147fa61431 |
| Source note | uspto-grants-1987_06 |