Potassium Carbonate → HCID 54398874, compound

HRID 652529Notes

Reaction equation

HRID 652529 reaction equation
Br[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12](=[O:14])[CH3:13])=[C:8]([CH2:15][CH2:16]C)[C:7]=1O.[OH:19][C:20]1[CH:21]=[C:22]([CH:28]=[CH:29][CH:30]=1)[C:23]([O:25][CH2:26][CH3:27])=[O:24].[C:31](=[O:34])([O-])[O-].[K+].[K+]>>[CH2:26]([O:25][C:23](=[O:24])[C:22]1[CH:28]=[CH:29][CH:30]=[C:20]([O:19][CH2:2][CH2:3][CH2:4][O:5][C:6]2[CH:11]=[CH:10][C:9]([C:12](=[O:14])[CH3:13])=[C:31]([OH:34])[C:7]=2[CH2:8][CH2:15][CH3:16])[CH:21]=1)[CH3:27]

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 24522Ethyl 3-hydroxybenzoateHCID 20197284HCID 20197284, compound

Product 1

HCID 54398874HCID 54398874, compoundYield 84%

Procedure

A mixture of 1.5 g of 1-[4-(3-bromopropoxy)-3-hydroxy-2-propylphenyl]ethanone, 0.79 g of ethyl 3-hydroxybenzoate and 1.0 g of potassium carbonate was allowed to react according to Example 79 to give 1.6 g (83% yield) of 3-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]benzoic acid ethyl ester, the title compound as an oil.

Workup

  1. customto react

Sources & evidence

ORD record
ord-b9b65d81b6d5463d9214f69689a7c084
Source dataset
uspto-grants-1987_06
Patent number
US04672066

Reaction notes

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