HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → HCID 20197534, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 20197533 | HCID 20197533 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20197534 | HCID 20197534 | 91.7% |
Reaction Steps
A solution of 3.5 g of 2,6-dimethyl-3-methoxycarbonyl-4-(3-nitrophenyl)-5-[2-(4-methoxycarbonylmethylaminophenyl)ethoxycarbonyl]-1,4-dihydropyridine hydrochloride salt in water (50 mL) is adjusted to pH 12 with NH4OH solution and extracted with methylene chloride. The methylene chloride is then evaporated to afford 3 g of 2,6-dimethyl-3-methoxycarbonyl-4-(3-nitrophenyl)-5-[2-(4-methoxycarbonylmethylaminophenyl)ethoxycarbonyl]-1,4-dihydropyridine as the free base.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04672071 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-1aa3661ab0d14edbaa8c9d0e42805de6 |
| Source note | uspto-grants-1987_06 |