4-Hydroxybenzaldehyde → 5-[(3,4-Dihydroxyphenyl)methylidene]imidazolidine-2,4-dione

Participants

Reaction Steps

5-(3,4-Dihydroxybenzylidene)-hydantoin was prepared in the same manner as in Example 4, except that 45.7 g (0.25 mol) of L-lysine.hydrochloride and 69.1 g (0.50 mol) of 3,4-dihydroxybenzaldehyde were used in lieu of glycine and p-hydroxybenzaldehyde, respectively. During the reaction, the pH of the reaction mixture was 9.4 to 9.2.

Provenance & Evidence