Chlorosuccinimide → HCID 18608222, compound

HRID 652572Notes

Reaction equation

HRID 652572 reaction equation
Cl[CH:2]1[CH2:14][O:13][C@H:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[C@@H:4]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH2:3]1.ClN1C(=O)CCC1=O.[Br:31]N1C(=O)CCC1=O>>[Br:31][CH:2]1[CH2:14][O:13][C@H:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[C@@H:4]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH2:3]1

Participants

4

Reactant 3

HCID 31398ChlorosuccinimideHCID 67184N-bromobutanimideHCID 18608223HCID 18608223, compound

Product 1

HCID 18608222HCID 18608222, compound

Procedure

10-Chloro Thromboxane B2Methyl Ester has been prepared using the same procedure except that N-chlorosuccinimide was substituted for N-bromosuccinimide. This 10-chloro compound can then be utilized in the same manner as the 10-bromo compound in the following examples.

Sources & evidence

ORD record
ord-de316dc23d6247e3bac737a09387f616
Source dataset
uspto-grants-1987_06
Patent number
US04672131

Reaction notes

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