Dimethylamine → HCID 13914720, compound

HRID 652584Notes

Reaction equation

HRID 652584 reaction equation
CN.CNC.C[NH:7][C:8]1[C:17]2[C:12](=[C:13]([Cl:22])[CH:14]=[C:15]([O:20][CH3:21])[C:16]=2[O:18][CH3:19])[N:11]=[C:10]([Cl:23])[N:9]=1.CN(C)C1C2C(=C(Cl)C=C(OC)C=2OC)N=C(Cl)N=1>>[NH2:7][C:8]1[C:17]2[C:12](=[C:13]([Cl:22])[CH:14]=[C:15]([O:20][CH3:21])[C:16]=2[O:18][CH3:19])[N:11]=[C:10]([Cl:23])[N:9]=1

Participants

5

Reactant 4

HCID 674DimethylamineHCID 6329MethylamineHCID 13914731HCID 13914731, compoundHCID 13914735HCID 13914735, compound

Product 1

HCID 13914720HCID 13914720, compound

Procedure

When, in the above procedure, methylamine or dimethylamine is employed in place of ammonia the corresponding 4-methylamino-2,8-dichloro-5,6-dimethoxyquinazoline and 4-dimethylamino-2,8-dichloro-5,6-dimethoxyquinazoline are obtained.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-27c6c4a73bd04a1c8e9f82c19a3cf958
Source dataset
uspto-grants-1987_06
Patent number
US04672116

Reaction notes

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