Hydrazine → HCID 13914722, compound

Participants

Reaction Steps

A mixture of 8-chloro-2,4,5,6-tetramethoxyquinazoline (1.0 g, 0.0035 moles), anhydrous hydrazine (5 ml, 0.16 moles) and methanol (50 ml) was stirred at reflux for 0.5 hours. The solvent was removed in vacuo and the residue was recrystallized from methanol. The resulting crystals were washed with methanol (20 ml) and dried under vacuum at 50° C. to afford the product (0.665 g), mp 166°-168° C.

Provenance & Evidence