反应详情

To a solution of 700 mg of β-(p-chlorophenyl)-α-methylene-γ-butyrolactone in 10 ml of toluene were added 0.51 ml of benzylmercaptan and one drop of triethylamine and the resulting mixture was kept at room temperature for 6 hours. After completion of the reaction, the reaction mixture was diluted with 100 ml of ethyl ether, washed with 10% aqueous sodium hydroxide and saturated saline, dried over magnesium sulfate and the solvent was distilled off. The crude product thus obtained was purified by a column chromatography to give 900 mg (yield 81%) of the title compound.

1. customAfter completion of the reaction
2. washwashed with 10% aqueous sodium hydroxide and saturated saline
3. dry with materialdried over magnesium sulfate
4. distillationthe solvent was distilled off
5. customThe crude product thus obtained
6. customwas purified by a column chromatography