Benzoyl chloride, 3-chloro- → 106106-52-9

HRID 652821Notes

Reaction equation

HRID 652821 reaction equation
[CH3:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=[O:8])[C:5]([NH2:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH:21]=1)[C:16](Cl)=O>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:16]([C:15]3[CH:19]=[CH:20][CH:21]=[C:13]([Cl:12])[CH:14]=3)[O:8][C:7](=[O:9])[C:6]=2[CH:10]=1

Participants

3

Reactant 2

HCID 69252Benzoyl chloride, 3-chloro-HCID 762552-Amino-5-methylbenzoic acid

Product 1

HCID 317080106106-52-9Yield 91.1%

Procedure

When the reaction conditions of Example 1 are employed but 11.3 g of 5-methylanthranilic acid and 13.1 g of 3-chlorobenzoyl chloride are used, 18.5 g (91%) of 6-methyl-2-(m-chlorophenyl)-4H-3,1-benzoxazin-4-one of melting point 160°-162° C. are obtained.

Workup

  1. customWhen the reaction conditions of Example 1

Sources & evidence

ORD record
ord-58edeff5b5eb461c9becc0d5c12e6111
Source dataset
uspto-grants-1987_06
Patent number
US04673740

Reaction notes

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