Sodium → HCID 13577513, compound

HRID 653011Notes

Reaction equation

HRID 653011 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([S:11][CH2:12][CH2:13]Cl)=[N:9][OH:10])=[CH:4][CH:3]=1.[Na]>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:11][CH2:12][CH2:13][O:10][N:9]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 5360545SodiumHCID 86740659HCID 86740659, compound

Product 1

HCID 13577513HCID 13577513, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Chloroethyl 4-chloro-N-hydroxybenzenecarboximidothioate (2.5 g, 0.01 mol) was cyclised with sodium (0.23 g) in ethanol (25 ml) as described in Example 2. 3-(4-Chlorophenyl)-5,6-dihydro-1,4,2-oxathiazine, mp 80.5°-81.5° C., was isolated. (Found: C, 50.16; H, 4.24; N, 6.44. C9H8ClNOS requires C, 50.58; H, 3.77; N, 6.55.)

Sources & evidence

ORD record
ord-9bbe3b3043eb435592798761ab764aec
Source dataset
uspto-grants-1987_06
Patent number
US04675044

Reaction notes

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