3-Chloro-1,2-propanediol → HCID 86151647, compound

HRID 653013Notes

Reaction equation

HRID 653013 reaction equation
[Cl:1][CH2:2][CH:3]([OH:6])[CH2:4][OH:5].[OH:7][CH:8]([CH2:20][OH:21])[CH2:9][N:10]([CH2:15][CH:16]([OH:19])[CH2:17][OH:18])[CH2:11][CH2:12][CH2:13][CH3:14]>>[Cl-:1].[CH2:11]([N+:10]([CH2:15][CH:16]([OH:19])[CH2:17][OH:18])([CH2:9][CH:8]([OH:7])[CH2:20][OH:21])[CH2:2][CH:3]([OH:6])[CH2:4][OH:5])[CH2:12][CH2:13][CH3:14]

Participants

3

Reactant 2

HCID 72903-Chloro-1,2-propanediolHCID 64552013,3'-(Butylazanediyl)di(propane-1,2-diol)

Product 1

HCID 86151647HCID 86151647, compound

Procedure

A fresh quantity of 66.3 g (0.6 mole) of 1-chloro-2,3-propanediol was added to the unpurified bis(2,3-dihydroxypropyl)-n-butylamine. These reagents were then brought to a temperature of 100° C. for 26 hours. Separation of the ammonium salt form was carried out in a methanolic medium with the aid of a cation exchange resin (Bio-Rad AG 50W-X8). In this way, 21.9 g of n-butyl-tris(2,3-dihydroxypropyl)ammonium chloride were obtained.

Workup

  1. customSeparation of the ammonium salt form

Sources & evidence

ORD record
ord-da2926ec961341b7ac72af209ab1687d
Source dataset
uspto-grants-1987_06
Patent number
US04675131

Reaction notes

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