Nitric Acid → HCID 70432462, compound

HRID 653065Notes

Reaction equation

HRID 653065 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH:10]([N:19]2[CH:23]=[CH:22][N:21]=[CH:20]2)[C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[Cl:18])=[O:9])=[CH:4][CH:3]=1.ClC1C=C(C=CC=1)C(OO)=[O:29].[N+:35]([O-:38])([OH:37])=[O:36]>C(Cl)Cl.CCOCC>[N+:35]([O-:38])([O-:37])=[O:36].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH:10]([N+:19]2[CH:23]=[CH:22][NH:21][CH:20]=2)[C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[Cl:18])(=[O:29])=[O:9])=[CH:4][CH:3]=1

Participants

6

Reactant 3

HCID 944Nitric AcidHCID 70297m-Chloroperbenzoic acidHCID 13937448HCID 13937448, compound

Product 1

HCID 70432462HCID 70432462, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent

Procedure

To a solution of 5 g (0.013 mole) of 1[α-(4-chlorophenylsulfinyl)-2,4-dichlorobenzyl]imidazole dissolved in 50 ml of methylene chloride is added 2.7 g (0.013 mole) of m-chloroperoxybenzoic acid in small portions at 0°. The reaction mixture is stirred at room temperature overnight. Concentrated nitric acid is added dropwise until the solution becomes acidic. When the reaction mixture is diluted with anhydrous ether, a white precipitate forms which is collected by filtration to give 4 g of desired product, mp 149°-9° (dec.).

Workup

  1. filtrationa white precipitate forms which is collected by filtration

Sources & evidence

ORD record
ord-6be3c88e02b44f429c8b86002470987e
Source dataset
uspto-grants-1987_06
Patent number
US04675316

Reaction notes

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