p-Chlorothiophenol → HCID 13937443, compound

HRID 653068Notes

Reaction equation

HRID 653068 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([SH:8])=[CH:4][CH:3]=1.[OH-].[Na+].[O:11]1[CH:13]([CH2:14][CH2:15][CH2:16][CH3:17])[CH2:12]1>O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:12][CH:13]([OH:11])[CH2:14][CH2:15][CH2:16][CH3:17])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 7815p-ChlorothiophenolHCID 14798Sodium HydroxideHCID 150362-Butyloxirane

Product 1

HCID 13937443HCID 13937443, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

To 28.9 g (0.2 mole) the p-chlorothiophenol and 8.0 g (0.2 mole) of sodium hydroxide in 100 ml of water is added 22.0 g (0.22 mole) of 1,2-epoxyhexane over 10 minutes. When addition is completed, the mixture is heated to reflux for 16 hours. The mixture is cooled, combined with 300 ml of water and the organic phase is separated.

Workup

  1. additionWhen addition
  2. temperaturethe mixture is heated
  3. temperatureto reflux for 16 hours
  4. temperatureThe mixture is cooled
  5. customthe organic phase is separated

Sources & evidence

ORD record
ord-b1f9d12b79824e34be609eba70338d45
Source dataset
uspto-grants-1987_06
Patent number
US04675316

Reaction notes

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