Triethylamine → HCID 13937444, compound

HRID 653069Notes

Reaction equation

HRID 653069 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH:10]([OH:15])[CH2:11][CH2:12][CH2:13][CH3:14])=[CH:4][CH:3]=1.[CH3:16][S:17](Cl)(=[O:19])=[O:18].C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH3:16][S:17]([O:15][CH:10]([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:9][S:8][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=1)(=[O:19])=[O:18]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 13937443HCID 13937443, compound

Product 1

HCID 13937444HCID 13937444, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To 42.0 g (0.172 mole) of 1-(p-chlorophenylthio)hexan-2-ol and 21.6 g (0.189 mole) of methane sulfonyl chloride in 100 ml of toluene is slowly added 20.8 g (0.206 mole) of triethylamine over a 1/2 hour period at less than 15° C. When the addition is completed, the mixture is stirred for 1/2 hour, and is allowed to warm to ambient temperature.

Workup

  1. customover a 1/2 hour
  2. customat less than 15° C
  3. additionWhen the addition

Sources & evidence

ORD record
ord-09dc857606b2432dbe959bc4b03d23ed
Source dataset
uspto-grants-1987_06
Patent number
US04675316

Reaction notes

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