Hydrochloric Acid → HCID 70443216, compound

HRID 653381Notes

Reaction equation

HRID 653381 reaction equation
O[C:2]1[CH:13]=[CH:12][C:5]([NH:6][C:7](=[O:11])[C:8](C)=[CH2:9])=[CH:4][CH:3]=1.Cl[S:15]([OH:18])(=[O:17])=[O:16].Cl.[OH-:20].[Na+]>C(Cl)Cl.O>[S:15]([OH:18])([OH:20])(=[O:17])=[O:16].[C:7]([NH:6][C:5]1[CH:12]=[CH:13][CH:2]=[CH:3][CH:4]=1)(=[O:11])[CH:8]=[CH2:9]

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 24638Chlorosulfonic acidHCID 29520Acrylanilide, 4'-hydroxy-2-methyl-

Product 1

HCID 70443216HCID 70443216, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 6344DichloromethaneSolvent

Procedure

An acrylanilide sulfate co-polymer was synthesized by first suspending 17.7 g (0.1 mol) of p-hydroxymethacrylanilide in 100 ml of methylene chloride in a suitable glass reaction vessel and then adding 12 g of chlorosulfonic acid to the suspension. Hydrogen chloride gas was observed evolving during the addition; and the reaction mass was mechanically stirred overnight at room temperature. The resultant product was dissolved in a solution of 60 g water and about 10 g of 50% sodium hydroxide, giving a pH of about 11; and methylene chloride was then separated by vacuum. A yield of about 75% of sulfated monomer, observed to be a viscous liquid, was then determined using nuclear magnetic resonance techniques.

Workup

  1. customin a suitable glass reaction vessel
  2. customgiving a pH of about 11
  3. customand methylene chloride was then separated by vacuum

Sources & evidence

ORD record
ord-7bcae51cbb154527b64e6f745062a3c1
Source dataset
uspto-grants-1987_06
Patent number
US04676911

Reaction notes

Loading…