HCID 54343509, compound → HCID 13112044, compound

HRID 653679Notes

Reaction equation

HRID 653679 reaction equation
[O:1]1CCO[CH:2]1[CH2:6][C:7]([CH3:13])([CH3:12])[CH2:8][CH2:9][C:10]#[N:11]>CC(C)=O.Cl.O>[CH:2]([CH2:6][C:7]([CH3:13])([CH3:12])[CH2:8][CH2:9][C:10]#[N:11])=[O:1]

Participants

5

Reactant 1

HCID 54343509HCID 54343509, compound

Product 1

HCID 13112044HCID 13112044, compoundYield 92.2%

Reagents, catalysts & solvents 3

HCID 180AcetoneSolventHCID 313Hydrochloric AcidSolventHCID 962WaterSolvent

Procedure

50 g of 5-(dioxolan-2-yl)-4,4-dimethylvaleronitrile, prepared in D], are dissolved in 1.3 1 of acetone in the presence of 140 ml of concentrated hydrochloric acid and 700 ml of water. The mixture is stirred at room temperature for 5 hours, the acetone is concentrated under vacuum and the residue is taken up with ether, washed with water and then evaporated to dryness to give 35 g of 5-formyl-4,4-dimethylvaleronitrile.

Workup

  1. concentrationthe acetone is concentrated under vacuum
  2. washwashed with water
  3. customevaporated to dryness

Sources & evidence

ORD record
ord-0a89ef16784e4571886d4271aad40821
Source dataset
uspto-grants-1992_07
Patent number
US05128359

Reaction notes

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