6-Chloro-3,4-dihydronaphthalene-1-carbonitrile → HCID 19882574, compound

HRID 653744Notes

Reaction equation

HRID 653744 reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([C:12]#[N:13])=[CH:7][CH2:6][CH2:5]2>CCO.Cl>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]([CH2:12][NH2:13])[CH2:7][CH2:6][CH2:5]2

Participants

4

Reactant 1

HCID 197932786-Chloro-3,4-dihydronaphthalene-1-carbonitrile

Product 1

HCID 19882574HCID 19882574, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolvent

HCID 702EthanolSolvent

Procedure

The product from Example 46 was catalytically reduced with Pt2O at 4 atms. pressure in EtOH and HCl, affording the desired product.

Sources & evidence

ORD record: ord-4479fb6ce22147e39a38992a0b8de32c
Source dataset: uspto-grants-1992_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05128362

Reaction notes

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