Diisopropyl Ether → HCID 14477683, compound

Participants

Role	Name	HCID	Charge
Reactant	Diisopropyl Ether	HCID 7914	—
Reactant	Phosphorus pentachloride	HCID 24819	—
Reactant	(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(fluoromethoxyimino)acetic acid	HCID 11031360	—
Solvent	Dichloromethane	HCID 6344	—
Product	HCID 14477683	HCID 14477683	39.4%

Reaction Conditions

Temperature	-10 °C

Reaction Steps

Phosphorus pentachloride (500 mg) was dissolved in dry methylene chloride (5 ml). After cooling the resulting solution to -10° C., 2-(5-amino-1,2,4-thidiazol-3-yl)-(Z)-2-fluoromethoxyiminoacetic acid (325 mg) was added and the resulting mixture was stirred at the same temperature for 30 minutes. Isopropyl ether (20 ml) was added to the reaction mixture, and the resulting precipitate was collected by filtration to obtain the target product (130 mg).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05128465
Source dataset	uspto-grants-1992_07
ORD ID	ord-bd6c73543a4542af9d693f1322ae92ca
Source note	uspto-grants-1992_07