5-Fluoro-2-hydroxy-3-nitro-N-(2,2,2-trifluoroethyl)benzamide → HCID 19888152, compound

Participants

Reaction Conditions

Reaction Steps

7.05 g (25 mmol) of 5-fluoro-2-hydroxy-3-nitrobenzoic acid-(2,2,2,-trifluoro-ethyl)amide is dissolved in 70 ml of ethanol, 5.65 (25 mmol) of SnCl2 ·H2O is added and the suspension is stirred for 2 hours at 70° C. The reaction mixture is then concentrated by evaporation to oil and used in the next reaction without purification.

Provenance & Evidence