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HRID654050

反应详情

EQUATION

反应方程式

HRID 654050 的结构方程式

REACTANTS

反应物

2
结构：Nc1ccc(F)c(C(F)(F)F)c1
HCID75377

alpha,alpha,alpha-4-Tetrafluoro-m-toluidine

C7H5F4N

结构：O=C(O)c1ccc(S(=O)(=O)Cl)cc1
HCID82385

Benzoic acid, 4-(chlorosulfonyl)-

C7H5ClO4S

PRODUCTS

生成物

1
结构：O=C(O)c1ccc(S(=O)(=O)Nc2ccc(F)c(C(F)(F)F)c2)cc1
HCID3699990

未命名化合物

收率 908.4%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

Analogously to Example 10, 2.21 g (10 mmol) of 4-chlorosulfonyl-benzoic acid is reacted with 1.79 g (10 mmol) of 4-fluoro-3-(trifluoromethyl)-aniline in pyridine and the crude product is crystallized from ethanol. 3.3 g=90.84 mmol of crystalline product is obtained. Melting point 238°-241° C.

WORKUP

后处理

  1. customthe crude product is crystallized from ethanol