Ethanol → HCID 19888170, compound

Participants

Reaction Steps

2 g (3.95 mmol) of 4-[N-(4-fluoro-3-trifluoromethylphenyl)sulfamoyl]-benzoic acid-(6-hydroxy-2,2-dimethyl-1,3-dioxepan-5-yl)-amide as well as 2 ml of cation exchanger in H. form are added to a solution of 10 ml of ethanol and 5 ml of distilled water and warmed for 90 minutes on the water bath. It is filtered from the exchanger, rewashed with distilled water, evaporated to dryness in a vacuum, and again taken up in water and by freeze-drying of this solution, 1.55 g=84.2% of the theoretical yield is obtained as an amorphous solid.

Provenance & Evidence