反应详情

Using the procedure described in Example 26, starting with 1 g of 6-hydroxy-5,6-dihydro-4-oxo-4H -pyrrolo[1,2-a]thieno[2,3-f][1,4]diazepine and 2 ml of ethyl acetoacetate, 0.7 g of 6-[1-(ethoxycarbonyl) -acetonyl]-5,6-dihydro-4-oxo-4H-pyrrolo[1,2-a]thieno -[2,3-f][1,4]diazepine was obtained in the form of white crystals, melting point 196° C. (ethyl ether).