hydroxylamine-O-sulfonic acid → HCID 19774688, compound

HRID 654294Notes

Reaction equation

HRID 654294 reaction equation
[CH:1]([CH:3]1[CH2:8][C:7](=[O:9])[CH:6]([C:10](=[O:13])[CH2:11][CH3:12])[C:5](=[O:14])[CH2:4]1)=O.[NH2:15]OS(O)(=O)=O>O>[O:14]=[C:5]1[CH:6]([C:10](=[O:13])[CH2:11][CH3:12])[C:7](=[O:9])[CH2:8][CH:3]([C:1]#[N:15])[CH2:4]1

Participants

4

Reactant 2

HCID 76284hydroxylamine-O-sulfonic acidHCID 15003567HCID 15003567, compound

Product 1

HCID 19774688HCID 19774688, compoundYield 77%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

30.7 g (0.16 mol) of 5-formyl-2-propionylcyclohexane-1,3-dione were introduced into 150 ml of distilled water and, at room temperature, 21.0 g (0.19 mol) of hydroxylamine-O-sulfonic acid were added. The mixture was then stirred at room temperature overnight. The precipitate was filtered off with suction, washed with water and dried. 23.8 g (71% of theory) of 3,5-dioxo-4-propionylcyclohexanecarbonitrile were obtained (melting point 70° to 74° C.).

Workup

  1. filtrationThe precipitate was filtered off with suction
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-53fa218a828944e890328accf7df209f
Source dataset
uspto-grants-1992_07
Patent number
US05130453

Reaction notes

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