Nitric Acid → HCID 18962546, compound

HRID 654388Notes

Reaction equation

HRID 654388 reaction equation
[N+:1]([O-:4])(O)=[O:2].C(OC(=O)C)(=O)C.[C:12]([O:15][C:16]1[C:21]([O:22][CH3:23])=[CH:20][C:19]([CH:24]([O:29][C:30](=[O:32])[CH3:31])[O:25][C:26](=[O:28])[CH3:27])=[CH:18][C:17]=1[O:33][CH3:34])(=[O:14])[CH3:13]>O>[C:12]([O:15][C:16]1[C:17]([O:33][CH3:34])=[CH:18][C:19]([CH:24]([O:25][C:26](=[O:28])[CH3:27])[O:29][C:30](=[O:32])[CH3:31])=[C:20]([N+:1]([O-:4])=[O:2])[C:21]=1[O:22][CH3:23])(=[O:14])[CH3:13]

Participants

5

Reactant 3

HCID 944Nitric AcidHCID 7918Acetic AnhydrideHCID 11659862HCID 11659862, compound

Product 1

HCID 18962546HCID 18962546, compoundYield 96%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
-15 °C

Procedure

32 cm3 of 100% nitric acid are cooled to -30° C. 100 cm3 of acetic anhydride then 40 g (0.123 mole) of 4-acetoxy-1-diacetoxymethyl-3,5-dimethoxybenzene are added with stirring. The temperature is left to increase to about -15° C. After stirring at this temperature for 30 minutes, the reaction mixture is poured into iced water. After filtration, washing with water and drying under vacuum, 43.8 g of the desired product are obtained in the form of a slightly yellow powder (yield=96%).

Workup

  1. waitThe temperature is left
  2. stirringAfter stirring at this temperature for 30 minutes
  3. filtrationAfter filtration
  4. washwashing with water
  5. dry with materialdrying under vacuum, 43.8 g of the desired product

Sources & evidence

ORD record
ord-a3253a0623384ae8bb197c425ae96838
Source dataset
uspto-grants-1992_07
Patent number
US05131911

Reaction notes

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