Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 11659862 | HCID 11659862 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 18962546 | HCID 18962546 | 96% |
Reaction Steps
32 cm3 of 100% nitric acid are cooled to -30° C. 100 cm3 of acetic anhydride then 40 g (0.123 mole) of 4-acetoxy-1-diacetoxymethyl-3,5-dimethoxybenzene are added with stirring. The temperature is left to increase to about -15° C. After stirring at this temperature for 30 minutes, the reaction mixture is poured into iced water. After filtration, washing with water and drying under vacuum, 43.8 g of the desired product are obtained in the form of a slightly yellow powder (yield=96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05131911 |
|---|
| Source dataset | uspto-grants-1992_07 |
|---|
| ORD ID | ord-a3253a0623384ae8bb197c425ae96838 |
|---|
| Source note | uspto-grants-1992_07 |
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