HCID 18962546, compound → HCID 18962544, compound

HRID 654389Notes

Reaction equation

HRID 654389 reaction equation
C([O:4][C:5]1[C:10]([O:11][CH3:12])=[CH:9][C:8]([CH:13](OC(=O)C)[O:14]C(=O)C)=[C:7]([N+:22]([O-:24])=[O:23])[C:6]=1[O:25][CH3:26])(=O)C>Cl>[CH3:26][O:25][C:6]1[C:7]([N+:22]([O-:24])=[O:23])=[C:8]([CH:9]=[C:10]([O:11][CH3:12])[C:5]=1[OH:4])[CH:13]=[O:14]

Participants

3

Reactant 1

HCID 18962546HCID 18962546, compound

Product 1

HCID 18962544HCID 18962544, compoundYield 97.9%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A suspension of 43 g (0.116 mole) of 4-acetoxy-1-diacetoxymethyl-3,5-dimethoxy-2-nitrobenzene in 500 cm3 of 2N hydrochloric acid is heated under reflux for 2 hours. The reaction mixture is left to return to ambient temperature, then the precipitate formed is filtered off. After washing with water and drying under vacuum, 25.8 g of the desired product is obtained in the form of a slightly yellow solid (yield=98%).

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 2 hours
  3. waitThe reaction mixture is left
  4. customto return to ambient temperature
  5. customthe precipitate formed
  6. filtrationis filtered off
  7. washAfter washing with water
  8. customdrying under vacuum

Sources & evidence

ORD record
ord-bce29021e6d94f5ea65ec3daef60f601
Source dataset
uspto-grants-1992_07
Patent number
US05131911

Reaction notes

Loading…