反应详情

3 g Phenyl isocyanide dichloride in 10 ml methylene chloride was treated at room temperature with a solution of 5.4 ml triethylamine and 1.7 g 2-hydroxymethylpiperidine in 20 ml methylene chloride. After 12 hours at room temperature, the mixture was washed with water, the organic phase was dried over magnesium sulphate, the solvent was distilled and the residue recrystallised from diisopropyl ether.

1. washthe mixture was washed with water
2. dry with materialthe organic phase was dried over magnesium sulphate
3. distillationthe solvent was distilled
4. customthe residue recrystallised from diisopropyl ether